DOI: 10.11607/prd.6441Pages 1-16, Language: EnglishPikos, Michael A / Miron, Richard J
Critical to the success of dental implants is the ability for clinicians to adequately obtain primary stability into host bone. Nevertheless, a number of conditions require dentists to perform multi-stage approaches to rebuild deficient bone volume prior to surgically placing dental implants. Thus, in many instances, implant placement cannot be achieved owing to a lack of primary implant stability. Recently, a novel mineral-organic resorbable bone adhesive (MORBA) has been the focus of intensive animal research demonstrating promising results for future clinical application. MORBA is a synthetic, injectable, self-setting, load-bearing adhesive biomaterial that exhibits osteopromotive properties and bonds bone-to-bone and bone-to-metal within a 10 minute period. Its unique novel formulation was developed from biomimetic proteins found in marine animal creatures (such as underwater sandcastle worms) that possess distinct adhesive properties underwater. A variety of animal studies have now confirmed excellent long-term results with the ability to offer clinicians immediate primary stability of dental implants using a biomaterial that is capable of fully resorbing within a 30 week period. The present case report demonstrates the use of MORBA in a first human patient on a non-restorable lower first molar. Following placement of a mobile 5.8mm Biohorizons implant, the use of MORBA was utilized to stabilize the implant. Following 3 months post-surgery, both clinical and CBCT radiographs demonstrated maintained implant stability. One year post-implant placement showed radiographic bone on the buccal surface of the implant with continued long-term stabilization of the implant. This case report now extends to 3 years whereby the use of MORBA, in an initially unstable situation, demonstrated excellent long-term follow-up in a first case report. Thus in conclusion, MORBA provided immediate implant stability, with resorbable characteristics leading to successful clinical long-term clinical outcomes up to 3 years. This innovative biomaterial will ultimately provide a more efficient solution to a critical problem in implant dentistry allowing for optimal primary stability during immediate implant placement and thus reducing the time and cost of current standards of care.