clinic for evaluation of a swelling of the right hard and soft palatal mucosa. The
patient denied any symptoms of pain or paresthesia in the area of concern (the hard
palate). The extraoral examination revealed no facial swelling or asymmetry, or lymphadenopathy.
Intraoral examination showed a 3 x 3 cm ulcerated sessile mass involving the posterior
two-thirds of the right hard palatal mucosa and one-third of the anterior right soft
palate (Figure 1). The swelling was firm and nontender on palpation. The adjacent teeth showed no
signs of caries or periodontal disease, were not mobile, and were not sensitive to
percussion.
Figure 1Initial clinical presentation of the right palatal mass, measuring 3 x 3 cm with irregular
surface ulcerations.
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References
American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw: 2014 update.
J Oral Maxillofac Surg. 2014; 72: 1938-1956
Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001.
Blood. 2006; 107: 265-276
The genomic landscape of Waldenstrom macroglobulinemia is characterized by highly recurring MYD88 and WHIM-like CXCR4 mutations, and small somatic deletions associated with B-cell lymphomagenesis.
Blood. 2014; 123: 1637-1646
Waldenstrom’s macroglobulinemia: clinical features, complications, and management.
J Clin Oncol. 2000; 18: 214-226
Waldenstrom macroglobulinaemia: presenting features and outcome in a series with 217 cases.
Br J Haematol. 2001; 115: 575-582
Diagnosis and management of Waldenstrom macroglobulinemia: Mayo stratification of macroglobulinemia and risk-adapted therapy (mSMART) guidelines.
Mayo Clin Proc. 2010; 85: 824-833
Ibrutinib in previously treated Waldenstrom’s macroglobulinemia.
N Engl J Med. 2015; 372: 1430-1440
Waldenstrom macroglobulinemia with extramedullary involvement at initial diagnosis portends a poorer prognosis.
J Hematol Oncol. 2015; 8: 74
A review of complications of odontogenic infections.
Natl J Maxillofac Surg. 2015; 6: 136-143
Differential diagnosis of the palatal mass.
Compendium. 1993; 14: 1222-1232
Oral squamous cell carcinoma: overview of current understanding of aetiopathogenesis and clinical implications.
Oral Dis. 2009; 15: 388-399
A guide for dental practitioners of common oral potentially malignant disorders.
CDA J. 2021; 49: 223-236
Trends in incidence of cancers of the oral cavity and pharynx: United States 2007-2016.
MMWR Morb Mortal Wkly Rep. 2020; 69: 433-438
Minor salivary gland neoplasms.
J Craniofac Surg. 2014; 25: e289-e291https://doi.org/10.1097/SCS.0000000000000723
Minor salivary gland tumors of the head and neck: Memorial Sloan Kettering experience: Incidence and outcomes by site and histological type.
Cancer. 2019; 125: 3354-3366
Biography
Dr. S. Sandhu is an oral medicine resident, Division of Oral Medicine and Dentistry, Brigham and Women’s Hospital, and an oral medicine resident, Department of Oral Medicine, Harvard School of Dental Medicine, 1620 Tremont St, Ste BC-3-028, Boston, MA 02120
Biography
Dr. P.K. Sandhu is a dental student, School of Dental Medicine, State University of New York, University at Buffalo, Buffalo, NY.
Biography
Dr. Sroussi is an associate professor, Division of Oral Medicine and Dentistry, Brigham and Women’s Hospital, and an associate professor, Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA.
Article Info
Publication History
Published online: November 23, 2021
Publication stage
In Press Corrected Proof
Footnotes
Disclosure. None of the authors reported any disclosures.
Diagnostic Challenge is published in collaboration with the American Academy of Oral and Maxillofacial Pathology and the American Academy of Oral Medicine.
Identification
DOI: https://doi.org/10.1016/j.adaj.2021.07.031
Copyright
(C) 2021 American Dental Association. All rights reserved.
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